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Medicinal mushrooms

- Improves symptoms of depression and anxiety
- Protects brain tissues
- Improves memory and learning
- Speeds up recovery from brain injury
- Promotes gut health
- Lowers blood sugar levels


Chaga (Inonotus obliquus)
- Lowers cholesterol levels
- Remedy for cancer
- Reduces inflammation
- Helps fight infection
- Reduces blood sugar levels

- Improves endurance
- Improves physical performance
- Anti-aging
- Helps fight cancer
- Lowers blood sugar levels

- Improves gut health
- Helps fight cancers
- Prevents obesity
- Improves immune function

- May lower blood pressure
- Promotes cardiovascular health
- May boost the immune system
- May help fight cancers
- Improves bone strength

- Supports immune system
- Fights cancer cells
- Lowers blood sugar levels
- Reduce cholesterol levels

- Portobello
- Reishii
- Oyster
- Agaricus
- Tremella
- Lai, P. L., Naidu, M., Sabaratnam, V., Wong, K. H., David, R. P., Kuppusamy, U. R., Abdullah, N., & Malek, S. N. (2013). Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. International journal of medicinal mushrooms, 15(6), 539–554. https://doi.org/10.1615/intjmedmushr.v15.i6.30
- Zhang, J., An, S., Hu, W., Teng, M., Wang, X., Qu, Y., Liu, Y., Yuan, Y., & Wang, D. (2016). The Neuroprotective Properties of Hericium erinaceus in Glutamate-Damaged Differentiated PC12 Cells and an Alzheimer's Disease Mouse Model. International journal of molecular sciences, 17(11), 1810. https://doi.org/10.3390/ijms17111810
- Ryu, S., Kim, H. G., Kim, J. Y., Kim, S. Y., & Cho, K. O. (2018). Hericium erinaceus Extract Reduces Anxiety and Depressive Behaviors by Promoting Hippocampal Neurogenesis in the Adult Mouse Brain. Journal of medicinal food, 21(2), 174–180. https://doi.org/10.1089/jmf.2017.4006
- Brandalise, F., Cesaroni, V., Gregori, A., Repetti, M., Romano, C., Orrù, G., Botta, L., Girometta, C., Guglielminetti, M. L., Savino, E., & Rossi, P. (2017). Dietary Supplementation of Hericium erinaceus Increases Mossy Fiber-CA3 Hippocampal Neurotransmission and Recognition Memory in Wild-Type Mice. Evidence-based complementary and alternative medicine : eCAM, 2017, 3864340. https://doi.org/10.1155/2017/3864340
- Mori, K., Obara, Y., Moriya, T., Inatomi, S., & Nakahata, N. (2011). Effects of Hericium erinaceus on amyloid β(25-35) peptide-induced learning and memory deficits in mice. Biomedical research (Tokyo, Japan), 32(1), 67–72. https://doi.org/10.2220/biomedres.32.67
- Lee, K. F., Chen, J. H., Teng, C. C., Shen, C. H., Hsieh, M. C., Lu, C. C., Lee, K. C., Lee, L. Y., Chen, W. P., Chen, C. C., Huang, W. S., & Kuo, H. C. (2014). Protective effects of Hericium erinaceus mycelium and its isolated erinacine A against ischemia-injury-induced neuronal cell death via the inhibition of iNOS/p38 MAPK and nitrotyrosine. International journal of molecular sciences, 15(9), 15073–15089. https://doi.org/10.3390/ijms150915073
- Li, I. C., Lee, L. Y., Tzeng, T. T., Chen, W. P., Chen, Y. P., Shiao, Y. J., & Chen, C. C. (2018). Neurohealth Properties of Hericium erinaceus Mycelia Enriched with Erinacines. Behavioural neurology, 2018, 5802634. https://doi.org/10.1155/2018/5802634
- Liu, J. H., Li, L., Shang, X. D., Zhang, J. L., & Tan, Q. (2016). Anti-Helicobacter pylori activity of bioactive components isolated from Hericium erinaceus. Journal of ethnopharmacology, 183, 54–58. https://doi.org/10.1016/j.jep.2015.09.004
- Wang, M., Konishi, T., Gao, Y., Xu, D., & Gao, Q. (2015). Anti-Gastric Ulcer Activity of Polysaccharide Fraction Isolated from Mycelium Culture of Lion's Mane Medicinal Mushroom, Hericium erinaceus (Higher Basidiomycetes). International journal of medicinal mushrooms, 17(11), 1055–1060. https://doi.org/10.1615/intjmedmushrooms.v17.i11.50
- Kim, S. P., Moon, E., Nam, S. H., & Friedman, M. (2012). Hericium erinaceus mushroom extracts protect infected mice against Salmonella Typhimurium-Induced liver damage and mortality by stimulation of innate immune cells. Journal of agricultural and food chemistry, 60(22), 5590–5596. https://doi.org/10.1021/jf300897w
- Liang, B., Guo, Z., Xie, F., & Zhao, A. (2013). Antihyperglycemic and antihyperlipidemic activities of aqueous extract of Hericium erinaceus in experimental diabetic rats. BMC complementary and alternative medicine, 13, 253. https://doi.org/10.1186/1472-6882-13-253
- Arata, S., Watanabe, J., Maeda, M., Yamamoto, M., Matsuhashi, H., Mochizuki, M., Kagami, N., Honda, K., & Inagaki, M. (2016). Continuous intake of the Chaga mushroom (Inonotus obliquus) aqueous extract suppresses cancer progression and maintains body temperature in mice. Heliyon, 2(5), e00111. https://doi.org/10.1016/j.heliyon.2016.e00111
- Sun, J. E., Ao, Z. H., Lu, Z. M., Xu, H. Y., Zhang, X. M., Dou, W. F., & Xu, Z. H. (2008). Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. Journal of ethnopharmacology, 118(1), 7–13. https://doi.org/10.1016/j.jep.2008.02.030
- Yang, M., et al. (2021). Lipid-Lowering Effects of Inonotus obliquus Polyaccharide In Vivo and In Vitro. Foods, 10(12):3085. https://doi.org/10.3390/foods10123085
- Sang, R., Sun, F., Zhou, H., Wang, M., Li, H., Li, C., Sun, X., Zhao, X., & Zhang, X. (2021). Immunomodulatory effects of Inonotus obliquus polysaccharide on splenic lymphocytes infected with Toxoplasma gondii via NF-κB and MAPKs pathways. Immunopharmacology and Immunotoxicology, 44(1), 129–138. https://doi.org/10.1080/08923973.2021.2017453
- Yi, X., Xi-zhen, H. & Jia-shi, Z. Randomized double-blind placebo-controlled clinical trial and assessment of fermentation product of Cordyceps sinensis (Cs-4) in enhancing aerobic capacity and respiratory function of the healthy elderly volunteers. Chin. J. Integr. Med. 10, 187–192 (2004). https://doi.org/10.1007/BF02836405
- Zou, Y., Liu, Y., Ruan, M., Feng, X., Wang, J., Chu, Z., & Zhang, Z. (2015). Cordyceps sinensis oral liquid prolongs the lifespan of the fruit fly, Drosophila melanogaster, by inhibiting oxidative stress. International journal of molecular medicine, 36(4), 939–946. https://doi.org/10.3892/ijmm.2015.2296
- Liu, W. C., Chuang, W. L., Tsai, M. L., Hong, J. H., McBride, W. H., & Chiang, C. S. (2008). Cordyceps sinensis health supplement enhances recovery from taxol-induced leukopenia. Experimental biology and medicine (Maywood, N.J.), 233(4), 447–455. https://doi.org/10.3181/0708-RM-230
- Jayachandran, M., Xiao, J., & Xu, B. (2017). A Critical Review on Health Promoting Benefits of Edible Mushrooms through Gut Microbiota. International Journal of Molecular Sciences, 18(9), 1934. https://doi.org/10.3390/ijms18091934
- Pallav, K., Dowd, S. E., Villafuerte, J., Yang, X., Kabbani, T., Hansen, J., Dennis, M., Leffler, D. A., Newburg, D. S., & Kelly, C. P. (2014). Effects of polysaccharopeptide fromTrametes Versicolorand amoxicillin on the gut microbiome of healthy volunteers. Gut Microbes, 5(4), 458–467. https://doi.org/10.4161/gmic.29558
- Finimundy, T. C., Dillon, A. J. P., Henriques, J. A. P., & Ely, M. R. (2014). A Review on General Nutritional Compounds and Pharmacological Properties of the <i>Lentinula edodes</i> Mushroom. Food and Nutrition Sciences, 05(12), 1095–1105. https://doi.org/10.4236/fns.2014.512119
- Dai, X., Stanilka, J. M., Rowe, C. A., Esteves, E. A., Nieves, C., Jr, Spaiser, S. J., Christman, M. C., Langkamp-Henken, B., & Percival, S. S. (2015). Consuming Lentinula edodes (Shiitake) Mushrooms Daily Improves Human Immunity: A Randomized Dietary Intervention in Healthy Young Adults. Journal of the American College of Nutrition, 34(6), 478–487. https://doi.org/10.1080/07315724.2014.950391
- Bak, W. C., Park, J. H., Park, Y. A., & Ka, K. H. (2014). Determination of Glucan Contents in the Fruiting Bodies and Mycelia of Lentinula edodes Cultivars. Mycobiology, 42(3), 301–304. https://doi.org/10.5941/MYCO.2014.42.3.301
- Phillips, K. M., Ruggio, D. M., Horst, R. L., Minor, B., Simon, R. R., Feeney, M. J., Byrdwell, W. C., & Haytowitz, D. B. (2011). Vitamin D and sterol composition of 10 types of mushrooms from retail suppliers in the United States. Journal of agricultural and food chemistry, 59(14), 7841–7853. https://doi.org/10.1021/jf104246z
- Mayell M. (2001). Maitake extracts and their therapeutic potential. Alternative medicine review : a journal of clinical therapeutic, 6(1), 48–60.
- Nanba, H., Kodama, N., Schar, D., & Turner, D. (2000). Effects of Maitake (Grifola frondosa) glucan in HIV-infected patients. Mycoscience, 41(4), 293–295. https://doi.org/10.1007/bf02463941
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